与饮食相关的疾病调解了口功能对老年人过早死亡的影响
Xindi Wei1, Xiaomeng Zhang1, Ruiying Chen1
1Department of Oral and Maxillofacial Implantology, Shanghai PerioImplant Innovation Center, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine; College of Stomatology, Shanghai Jiao Tong University; National Center for Stomatology; National Clinical Research Center for Oral Diseases; Shanghai Key Laboratory of Stomatology; Shanghai Research Institute of Stomatology, Shanghai, China.
Journal of periodontal research
|August 13, 2024
概括
拥有不到四个功能性牙单元 (FTU) 的老年人面临过早死亡的风险翻了一番. 糖尿病和高血压等疾病部分解释了这种联系,强调了口腔健康对长寿的重要性.
科学领域:
- 老年学是指老年学的学科.
- 公共卫生 公共卫生
- 牙科医学 牙科医学
背景情况:
- 口腔健康不佳,以有限的功能牙单位 (FTU) 为特征,是死亡的潜在风险因素.
- FTU与过早死亡之间的确切关联,以及潜在的机制,需要进一步阐明.
研究的目的:
- 调查功能牙单位 (FTU) 数量与老年人过早死亡之间的关联.
- 探索饮食相关疾病在FTU和过早死亡之间关系中的调解作用.
主要方法:
- 分析了2009-2018年国家健康和营养检查调查 (NHANES) 和国家死亡指数 (NDI) 的数据.
- 定义FTU是前牙和牙区域对立的自然牙和人工牙的对.
- 应用加权后勤回归,倾向得分匹配 (PSM) 和调解分析来评估关联和机制.
主要成果:
- 60-74岁的0-3FTU的个体,与10-12FTU的个体相比,早期死亡的几率明显更高 (OR=2.142).
- 在数据归算 (OR=2.115) 和PSM (OR=2.196) 之后,这种关联仍然显著.
- 糖尿病 (5.089%) 和高血压 (8.437%) 部分介导了低FTU和过早死亡之间的关系.
结论:
- 低FTU表示的功能受损与老年人过早死亡风险增加有关.
- 低FTU (0-3) 与过早死亡有显著的相关性,糖尿病和高血压发挥了部分调解作用.
- 建议进行进一步的纵向研究来证实这些发现.
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