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Updated: Jun 17, 2025

Assessment of Vascular Tone Responsiveness using Isolated Mesenteric Arteries with a Focus on Modulation by Perivascular Adipose Tissues
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内甲素-1降低核因子红色素2相关因子-2的调节,并有助于肥胖的周围血管脂肪组织功能障碍

Anna Flavia R Lima1, Daniel Rodrigues1, Mirele R Machado1

  • 1Department of Pharmacology, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto, SP, Brazil.

Clinical science (London, England : 1979)
|August 13, 2024
PubMed
概括

肥胖会通过增加内甲素-1 (ET-1) 来损害周血管脂肪组织 (PVAT) 功能,从而降低抗氧化防御和血管保护. 用Bosentan阻断ET-1受体恢复了PVAT功能,突出了与肥胖相关的血管问题的治疗目标.

关键词:
末端蛋白-1-1的使用肥胖 肥胖 肥胖 肥胖 肥胖 肥胖 肥胖 肥胖氧化应激是一种氧化应激.周围的周周脂肪组织组织.

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