估计的葡萄糖处置率控制水平和中年和老年成人中风发病率之间的关联
Jiangnan Yao1, Feng Zhou2, Lingzhi Ruan3
1College of Nursing, Wenzhou Medical University, Wenzhou, China.
Journal of diabetes
|August 13, 2024
概括
控制不良的估计葡萄糖处理率 (eGDR) 显著增加了老年人中风风险. 监测eGDR水平可以帮助识别高风险中风的个体.
科学领域:
- 代谢健康和脑血管疾病研究.
- 慢性疾病和衰老的流行病学.
背景情况:
- 胰岛素耐药性是一个日益严重的健康问题.
- 估计的葡萄糖处置率 (eGDR) 是一种已验证的胰岛素耐药性的标志物.
- 关于eGDR控制水平与中风发病率之间的关联,研究有限.
研究的目的:
- 调查不同级别的eGDR控制与中风发病率之间的关联.
- 探索eGDR控制对中年和老年人中风事件的影响.
主要方法:
- 利用了中国长度健康与退休研究 (CHARLS) 的数据.
- 使用K-means集群分析来对eGDR控制级别进行分类.
- 应用后勤回归和限制性立方线回归来分析eGDR和中风发病率之间的关联.
主要成果:
- 总共有4790名参与者被分析,其中304人 (6.3%) 在3年内发生中风.
- 较高的eGDR类 (控制不良和最差) 与控制最好的类相比,显示中风的几率比率显著增加.
- 限制性立方脊线分析显示,eGDR变化与中风发生之间存在线性相关性.
- 腰围和高血压被确定为与eGDR相关的发生性中风的关键预测因素.
结论:
- 控制不良的eGDR水平与中年和老年人中风风险的增加有显著联系.
- 定期监测eGDR变化可以作为识别高风险中风个体的早期指标.
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