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Updated: Oct 28, 2025

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通过mRNA显示发现乙烯循环的宏循环共价抑制剂

Tong Lan1, Cheng Peng1, Xiyuan Yao1

  • 1Department of Chemistry, The University of Chicago, Chicago, Illinois 60637, United States.

Journal of the American Chemical Society
|August 13, 2024
PubMed
概括

我们开发了一个新的mRNA显示平台, 这种方法确定了TEV蛋白酶的强大抑制剂,包括具有前所未有的强度的独特宏环.

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相关概念视频

RNA Interference01:23

RNA Interference

RNA interference (RNAi) is a process in which a small non-coding RNA molecule blocks the post-transcriptional expression of a gene by binding to its messenger RNA (mRNA) and preventing the protein from being translated.
This process occurs naturally in cells, often through the activity of genomically-encoded microRNAs. Researchers can take advantage of this mechanism by introducing synthetic RNAs to deactivate specific genes for research or therapeutic purposes. For example, RNAi could be used...
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