中枢神经系统在类风湿性疾病中的表现
Svitlana Smiyan1, Roman Komorovsky2, Bohdan Koshak1
12nd Department of Internal Medicine, Ivan Horbachevsky Ternopil National Medical University, Ternopil, Ukraine.
Rheumatology international
|August 13, 2024
概括
神经病学家和风湿病学家必须合作,在风湿性疾病中管理中枢神经系统 (CNS) 问题. 了解自身免疫标记物和治疗副作用是改善患者治疗结果的关键.
科学领域:
- 类风湿病学 类风湿病学
- 神经学 神经学
- 免疫学 免疫学 免疫学
背景情况:
- 神经病学家在风湿性疾病管理中的作用正在增长.
- 中枢神经系统 (CNS) 的参与是自身免疫性类风湿性疾病的重要并发症.
- 风湿病学家和神经病学家之间的合作是至关重要的.
研究的目的:
- 审查主要自身免疫性类风湿性疾病中中枢神经系统的表现.
- 要突出自身免疫标记物,全身炎症和神经损伤之间的联系.
- 强调认识到与治疗有关的神经系统不良事件的重要性.
主要方法:
- 关于自身免疫性类风湿性疾病中中枢神经系统表现的文献综述.
- 对自身免疫标志物和中枢神经系统损伤的新发现的分析.
- 讨论与生物疗法相关的神经学不良事件.
主要成果:
- 常见的中枢神经系统表现包括中风,脑膜大脑炎,脑膜炎,骨髓病变,精神病,胆,和头痛.
- 特定的自身免疫标志物与中枢神经系统损伤直接相关,表明有重要的炎症成分.
- 生物疗法可以引起神经症状,需要仔细评估.
结论:
- 有效管理类风湿性疾病需要解决中枢神经系统参与的问题.
- 涉及风湿病学家和神经病学家的多学科方法对于最佳的患者护理至关重要.
- 进一步了解神经风湿界面将改善患者的治疗结果.
更多相关视频
08:47Induction of Experimental Autoimmune Encephalomyelitis in Mice and Evaluation of the Disease-dependent Distribution of Immune Cells in Various Tissues
Published on: May 8, 2016
23.7K
09:35Isolating Central Nervous System Tissues and Associated Meninges for the Downstream Analysis of Immune cells
Published on: May 19, 2020
9.2K
相关概念视频
T Cell Types and Functions
964
When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
964
Disorders of the Nervous Tissue
1.1K
Nervous tissue is a vital component of the human body's communication system, enabling us to perceive and respond to stimuli. However, like all other tissues, it is vulnerable to disorders and diseases that can significantly impact our neurological functioning.
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...
1.1K
Autoimmune Disorders
398
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
Concept and Mechanism of Autoimmune Diseases
The immune...
398
Disorders of the Autonomic Nervous System
590
The autonomic nervous system (ANS) is an intricate network of nerves that controls functions such as the regulation of heart rate, digestion, and blood pressure regulation. When this system malfunctions, it can lead to various disorders that affect multiple bodily functions. One common feature of many autonomic disorders is the involvement of smooth blood vessels, which play a crucial role in regulating blood flow throughout the body.
Raynaud's disease, also known as Raynaud's...
Raynaud's disease, also known as Raynaud's...
590
Neural Regulation
39.2K
Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
39.2K
Pulmonary Tuberculosis III
316
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
316
