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Updated: Jun 17, 2025

Visualizing Axonal Growth Cone Collapse and Early Amyloid β Effects in Cultured Mouse Neurons
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由Psen1突变引起的皮质神经退行是独立于Aβ的

Kuo Yan1, Chen Zhang1, Jongkyun Kang1

  • 1Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.

Proceedings of the National Academy of Sciences of the United States of America
|August 13, 2024
PubMed
概括

在PSEN基因中的家族性阿尔茨海默病突变会导致独立于粉样β (Aβ) 的神经退行. 这表明一种功能丧失机制,而不是Aβ增加,在PSEN突变中驱动疾病进展.

关键词:
这就是为什么APP APP APP APP阿尔茨海默氏症是阿尔茨海默氏症的一种疾病.普雷西尼林是一种素.灭症 (apoptosis) 是一种死亡的过程.滑症是一种滑性疾病.

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