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LTβR 激动性通过调节瘤微环境促进抗瘤免疫反应

Disi An1, Guoying Chen1, Wei-Yi Cheng1

  • 1Regeneron Pharmaceuticals, Inc., Tarrytown, New York.

Cancer research
|August 13, 2024
PubMed
概括

淋巴毒素β受体 (LTβR) 信号传递促进瘤中高内皮静脉 (HEV) 和三级淋巴状结构 (TLS) 的形成. 这增强了T细胞的反应,提高了免疫治疗对抗癌症的疗效.

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