逆行月经的潜在解剖学决定因素:一个全面的叙事审查
Paolo Vercellini1, Martina Piccini2, Francesca Caprara2
1Academic Centre for Research on Adenomyosis and Endometriosis, Department of Clinical Sciences and Community Health, Università degli Studi, Milan, Italy; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Reproductive biomedicine online
|August 13, 2024
概括
子宫的解剖学因素,包括子宫,输卵管和子宫肌,影响子宫内膜异位症的风险. 与腺菌症相关的肌肉膜异常显示出与子宫内膜异常发展的最强相关性.
科学领域:
- 妇科 妇科 妇科 妇科
- 生殖医学 生殖医学
- 手术解剖学手术解剖学
背景情况:
- 子宫内膜异位症是一种子宫组织在子宫外生长的情况.
- 反向性月经是对子宫内膜异位症发展的一个建议机制.
- 桑普森的百年老假设确定了三个关键的子宫结构,影响逆行性月经和子宫内膜异位症风险.
研究的目的:
- 批判性地评估现有的关于宫,宫内管道和宫特征在子宫内膜异位症风险中的作用的数据.
- 评估支持桑普森关于这些解剖变量的假设的证据.
主要方法:
- 系统审查和批判性评估过去40年发表的研究.
- 对调查子宫特定解剖特征与子宫内膜异位症之间的关联的研究进行分析.
主要成果:
- 有证据表明,宫通道直径,孔径狭窄和组织度可能起作用.
- 室内输卵管形态与子宫内膜异位症的频率有关.
- 肌肉膜异常,往往表明腺菌,最一致地与子宫内膜异常有关,可能会通过增加逆行性月经来导致并导致其.
结论:
- 宫和输卵管因素与子宫内膜异位症风险有一定的关联.
- 肌肉膜异常和早期发病的腺菌症被强烈认为是子宫内膜异常的前体.
- 需要进一步的研究来探索初潮,子宫肌肉变化,逆行性月经和子宫内膜异位症风险之间的联系.
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