在慢性胰腺炎中,内镜超声波特征与异位胰腺功能之间的相关性
Caterina Stornello1, Chiara Deli2, Giuseppe Dell'Anna2
1Pancreato-Biliary Endoscopy and Endosonography Division, Pancreas Translational & Clinical Research Center, San Raffaele Scientific Institute IRCCS, Vita-Salute San Raffaele University, Milan, Italy; Section of Gastroenterology & Hepatology, Department of Health Promotion Sciences Maternal and Infant Care, Internal Medicine and Medical Specialties, PROMISE, University of Palermo, Italy.
透视超声波 (EUS) 发现,特别是主要胰腺管化,有助于预测慢性胰腺炎 (CP) 中的胰腺外分泌功能缺陷 (PEI). 其他EUS特征在评估外分泌功能时具有有限的实用性.
科学领域:
- 胃肠病学 胃肠病学
- 医疗成像医学成像
- 胰腺学 胰腺学
背景情况:
- 内镜超声波 (EUS) 对于使用罗斯蒙特分类 (RC) 的早期慢性胰腺炎 (CP) 诊断至关重要.
- 有限的数据存在于EUS发现和胰腺外分缺陷 (PEI) 之间的相关性.
研究的目的:
- 调查CP患者中EUS发现和PEI之间的相关性.
- 评估罗斯蒙特分类 (RC) 在预测PEI时的准确性.
主要方法:
- 对128名确定的/可能的CP患者进行了回顾性单心队列研究 (2018-2022年).
- 在诊断后12个月内进行的EUS和表皮功能测试 (便弹性酶/静脉反应).
- 后勤回归,等级相关性和ROC分析用于评估PEI预测的EUS特征和RC准确性.
主要成果:
- 69.5%的患者患有PEI.
- 主胰腺管 (MPD) 化是唯一与增加PEI风险相关的RC标准 (OR 2.92).
- 在预测PEI方面,RC显示中度准确性 (AUROC 0.62),与便弹性酶的反相关性较弱.
结论:
- 在EUS上的主要胰腺管化是CP中PEI的有价值的预测指标.
- 罗斯蒙特分类中的其他EUS发现对于评估外分泌功能具有有限的有用性.
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