改变野生种群的特征和命运,其中孟德尔的DNA序列修改了亚ليل帆

Michelle L Johnson1, Bruce A Hay2, Maciej Maselko3

  • 1Division of Biology and Biological Engineering, California Institute of Technology, 1200 East California Boulevard, MC156-29, Pasadena, CA, 91125, USA.

Nature communications
|August 13, 2024
PubMed
概括

对野生种群而言,Allele Sails提供了一种新的基因组编辑方法. 这种方法限制了基因修饰组件的传播,有可能克服与基因驱动相关的监管和社会问题.

相关概念视频

Mutation, Gene Flow, and Genetic Drift01:09

Mutation, Gene Flow, and Genetic Drift

In a population that is not at Hardy-Weinberg equilibrium, the frequency of alleles changes over time. Therefore, any deviations from the five conditions of Hardy-Weinberg equilibrium can alter the genetic variation of a given population. Conditions that change the genetic variability of a population include mutations, natural selection, non-random mating, gene flow, and genetic drift (small population size).
58.3K
Gene Conversion02:08

Gene Conversion

Other than maintaining genome stability via DNA repair, homologous recombination plays an important role in diversifying the genome. In fact, the recombination of sequences forms the molecular basis of genomic evolution. Random and non-random permutations of genomic sequences create a library of new amalgamated sequences. These newly formed genomes can determine the fitness and survival of cells. In bacteria, homologous and non-homologous types of recombination lead to the evolution of new...
9.7K
In-vitro Mutagenesis01:16

In-vitro Mutagenesis

To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.
13.9K
Gene Flow02:39

Gene Flow

Gene flow is the transfer of genes among populations, resulting from either the dispersal of gametes or from the migration of individuals.
35.0K