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Updated: Jun 17, 2025

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在社区队列中,抗抑郁药治疗期间和之后脂肪标志物的长期变化

Jessica Mwinyi1, Marie-Pierre F Strippoli2, Sofia H Kanders1,3

  • 1Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.

Translational psychiatry
|August 13, 2024
PubMed
概括

长期使用抗抑郁药,特别是SSRI和TCA,与体重增加有关. 然而,在停止服用这些药物后,脂肪标志物可能会恢复正常.

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Atypical antidepressants, including bupropion (Wellbutrin), mirtazapine (Remeron), nefazodone (Serzone), trazodone (Desyrel), and vilazodone (Viibryd), offer unique mechanisms of action. Bupropion weakly inhibits dopamine and norepinephrine reuptake, aiding depression treatment and smoking cessation, with a low risk of sexual dysfunction. Mirtazapine enhances serotonin and norepinephrine neurotransmission, leading to sedation, increased appetite, and weight gain. As a result, it helps treat...
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