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Updated: Jun 17, 2025

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综合转录组学和基于结构的药物重新定位识别了具有蛋白酶体抑制特性的药物

Peter Larsson1,2, Maria Cristina De Rosa3, Benedetta Righino3

  • 1Department of Oncology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. peter.larsson.3@gu.se.

Scientific reports
|August 13, 2024
PubMed
概括

计算型药物基因组学确定了六种具有蛋白酶体抑制剂 (PI) 特性的新化合物. 这些化合物通过向蛋白质体活性,显示出药物重新定位和癌症治疗的潜力.

关键词:
抗瘤药剂是一种抗瘤药剂.药物发现 药物发现药物作用机制-药物作用机制药物查是指对药物进行查.分子对接是分子对接.转录的签名 转录的签名未描述的蛋白酶体抑制剂

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