向着自由手光学超声波成像的临床应用
Fraser T Watt1,2, Eleanor C Mackle3,4, Edward Z Zhang3,4
1Wellcome / EPSRC Centre for Interventional and Surgical Sciences, University College London, London, UK. fraser.watt.20@ucl.ac.uk.
Scientific reports
|August 13, 2024
概括
这项研究引入了一个新的自由手光学超声波 (OpUS) 成像平台,具有改进的探针设计. 改进后的系统提供了更好的超声波透率和成像质量,使OpUS更接近临床使用.
科学领域:
- 生物医学工程 生物医学工程
- 光学成像技术的成像
- 医疗器械 医疗器械
背景情况:
- 自由手光学超声波 (OpUS) 成像是一种用于非侵入性可视化的新兴技术.
- 之前的OpUS系统在超声波透度,图像质量和临床适用性方面面临限制.
- 显然,需要改进临床翻译的OpUS平台.
研究的目的:
- 介绍一款具有改进的探头设计的新型自由手OpUS成像平台.
- 为了提高超声波的透深度,减少成像工件.
- 推进自由手的OpUS技术的临床翻译.
主要方法:
- 开发了一种新型的自由手OpUS探头,使用光学波导用于超声波场成型.
- 集成扩展光纤捆绑,以增加系统的多功能性.
- 实施了坚固的探头设计,配有保护元素,以提高操作性和耐用性.
- 使用幻影研究和第一个多参与者体内成像研究的演示.
主要成果:
- 新型OpUS探测器展示了改进的超声波场塑造,以提高透率.
- 与以前的设计相比,该系统展示了减少的成像工件,并改善了整体图像质量.
- 在人类参与者中成功实现了体内成像,验证了平台的潜力.
结论:
- 开发的自由手的OpUS成像平台代表了光学超声波技术的重大进步.
- 改进的探针设计和移动控制台解决了关键限制,为临床采用铺平了道路.
- 这项工作标志着自由手OpUS成像的临床翻译取得了实质性的进展.
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