水管吸烟与冠状动脉疾病的存在和严重程度有关:一项倾向性得分匹配研究
Farzad Masoudkabir1,2,3, Sepehr Nayebirad4, Majid Yousefi4
1Cardiac Primary Prevention Research Center, Cardiovascular Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran. farzad.masoudkabir@gmail.com.
BMC cardiovascular disorders
|August 13, 2024
概括
水管吸烟 (WPS) 与冠状动脉疾病 (CAD) 的更高可能性和动脉样硬化的严重程度增加有关. 即使考虑到年龄,性别和吸烟习惯,这种联系仍然存在.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 在全球范围内,烟斗吸烟 (WPS) 的流行率正在上升.
- WPS对心血管健康构成风险.
- WPS与冠状动脉疾病 (CAD) 之间的关联需要进一步调查.
研究的目的:
- 探索烟斗吸烟与冠状动脉疾病 (CAD) 的存在和严重程度之间的联系.
- 评估WPS是否是CAD的独立风险因素.
主要方法:
- 对接受冠状动脉血管学检查的8699名患者进行了回顾性分析.
- 倾向分数匹配 (1:4) 将380名水管吸烟者与1520名非吸烟者进行比较.
- 冠状动脉疾病 (CAD) 定义为狭窄 ≥50%;严重程度通过Gensini评分进行评估.
主要成果:
- 与非吸烟者相比,吸烟烟的人患病率更高 (OR:1.29;P=0.021).
- 在患有动脉样硬化冠状动脉疾病 (P=0.014) 的患者中,WPS与更高的根西尼分数 (自然对数) 相关.
结论:
- 水管吸烟可能会独立增加患冠状动脉疾病 (CAD) 的风险.
- 在患有动脉样硬化症的患者中,WPS可能会导致更严重的疾病,由更高的根西尼分数表明.
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