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Updated: Jun 17, 2025

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
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Published on: June 21, 2018

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在门德尔随机化中使用基因变异的聚类来调查由一个共同的风险因素导致多病症的潜在因果途径

Xiaoran Liang1, Ninon Mounier1, Nicolas Apfel2

  • 1Department of Clinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, UK.

Genetic epidemiology
|August 14, 2024
PubMed
概括

这项研究介绍了MR-AHC,这是一种用于孟德尔随机化分析的新方法. 它确定了基因集群,揭示了2型糖尿病和骨关节炎等复杂疾病的明显因果途径.

关键词:
门德尔的随机化集群分析分析集群分析不同质的因果关系效应.一个层次的集群.多重病态性多重病态性强大的MR MR.

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