权衡你的选择 - - 胃内气球与半黄胺相比
Kevin Choy1, Danielle Abbitt2, Alexandra Kovar2
1Department of Surgery, University of Colorado School of Medicine, 12631 E 17Th Ave, C-305, Aurora, CO, 80045, USA. Kevin.Choy@CUAnschutz.Edu.
Surgical endoscopy
|August 14, 2024
概括
在退伍军人中,类似葡萄糖类-1-受体激动剂 (GLP1RA) 像塞马格卢提德一样显示出比胃内气球 (IGB) 更可持续的体重减轻. 虽然IGB提供了更快的初始减肥,但GLP1RA促进了持续的减肥,并防止在治疗后一年恢复体重.
科学领域:
- 减肥医学 减肥医学
- 内分泌学 在内分泌学.
- 代谢健康 代谢健康
背景情况:
- 肥胖影响了超过一半的美国人和高达78%的美国退伍军人.
- 胃内气球 (IGB) 促进外科手术期间的体重减轻,但往往会在切除后恢复体重.
- 类似葡萄糖-1受体激动剂 (GLP1RA) 是持续体重管理干预后的潜在解决方案.
研究的目的:
- 为了比较用GLP1RA治疗的退伍军人和接受IGB治疗的退伍军人之间的长期体重恢复.
- 评估GLP1RA作为减肥干预后可持续减肥策略的有效性.
主要方法:
- 一项回顾性审查将接受IGB (1/2019-1/2023) 的患者与在VA医疗中心启动GLP1RA (6/2021-8/2022) 的患者进行了比较.
- 所有参与者都参加了一项多学科的减肥计划,持续至少12周.
- 体重变化在0,3,6和12个月被跟踪,不包括先前做过减肥手术或不完整数据的患者.
主要成果:
- 与IGB相比,塞马格卢提德 (GLP1RA) 在12个月后导致体重恢复较少.
- 一年后,IGB患者平均恢复了3公斤 (23.6%),而塞马格卢提德患者继续减肥.
- 在最初的6个月内,IGB的初始体重减轻速度更快 (-12.7公斤),而不是塞马格卢提德 (-9.4公斤).
结论:
- 胃内气球导致更快的初始体重减轻,但类似葡萄糖-1受体激动剂显示出优越的长期体重控制.
- 在去除IGB后,重量恢复是一个重要的问题,即使有全面的减肥计划.
- 对IGB和GLP1RA联合治疗的进一步研究可能会提供最佳的长期减肥结果.
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