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Updated: Jun 17, 2025

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准备,表征和评估Nintedanib无形固体分散物与增强的口服生物利用性

Shuyin Liu1,2, Hui Chen2, Feng Zhou2

  • 1Cixi Biomedical Research Institute, Wenzhou Medical University, Cixi, 315300, China.

AAPS PharmSciTech
|August 14, 2024
PubMed
概括

这项研究使用热挤出 (HME) 开发了宁泰达尼布 (NDNB) 的无形固体分散 (ASD),以提高口服生物可用性. 结果的NDNB-ASD显示与原始药物和商业囊相比,溶解和体内吸收显著增强.

关键词:
无形固体分散的无形固体分散热挤出 热挤出任天堂Danib 在线播放口服生物可用性 口服生物可用性

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