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Updated: Jun 17, 2025

Characterize Disease-related Mutants of RAF Family Kinases by Using a Set of Practical and Feasible Methods
07:49

Characterize Disease-related Mutants of RAF Family Kinases by Using a Set of Practical and Feasible Methods

Published on: July 17, 2019

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效应器结合顺序改变了膜上的KRAS微分化:对RAS介导的RAF激活的新见解

Soo-Yeon Lee1, Hyun-Jong Eun2, Ki-Young Lee3

  • 1Department of Pharmacy, College of Pharmacy and Institute of Pharmaceutical Sciences, CHA University, Pocheon-si, Gyeonggi-Do, 11160, Republic of Korea.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|August 14, 2024
PubMed
概括

在结构上阐明了对癌症至关重要的RAS-RAF复合体形成. RAF结合改变了KRAS二分化,揭示了RAF激活和信号复合组合的新机制.

关键词:
在KRAS的二元化过程中.在RBD-CRD中使用RBD-CRD.一个纳米光盘.增强了对磁性放松,增强了对磁性放松.连续结合的连续结合

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Fully Processed Recombinant KRAS4b: Isolating and Characterizing the Farnesylated and Methylated Protein07:08

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