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在甲状腺囊细胞模式分析的有效性细针吸收细胞学评估评估

Sasidharannair Chandrakumari Abilash¹, Singaravelu Shree Lakshmi Devi², Sinha Pammy³

¹Department of Pathology, Windsor University School of Medicine, Cayon, St. Kitts, West Indies.

Annals of African medicine

|August 14, 2024

概括

精细针吸收细胞学 (FNAC) 通过分析卵泡细胞结构,有效地诊断甲状腺病变. 这种方法补充了形态学,提高了瘤和非瘤疾病的诊断准确度.

科学领域:

病理学病理学病理学
细胞病理学细胞病理学
内分泌学在内分泌学.

背景情况:

精细针吸收细胞学 (FNAC) 是甲状腺病变的主要诊断工具.
挑战包括样本不足和重叠的细胞特征.
组织病理相关性对于验证FNAC发现至关重要.

研究的目的:

为了评估甲状腺病变的FNAC的诊断准确性.
在FNAC解释中评估毛囊细胞结构模式的实用性.
为了将FNAC发现与组织病理学诊断相关联.

主要方法:

一项涉及110例甲状腺损伤病例的横截面研究.
细胞病理学家分析了毛囊细胞结构 (大毛囊细胞,小毛囊细胞,乳头细胞,状细胞,集群细胞,分散细胞).
细胞学诊断与组织病理学发现相关.

主要成果:

特定的建筑模式与诊断有关:宏状 (状, 80.26%),微状 (状瘤, 72.2%),乳头状 (乳头状甲状腺癌, 62.5%).
在瘤病变中FNAC的高诊断准确性:灵敏度为92.59%,特异性为97.59%.
在慢性淋巴细胞性甲状腺炎和卵泡性瘤中观察到的形模式.

结论:

FNAC是用于初始甲状腺损伤评估的经济有效,快速和明确的工具.
分析卵泡细胞结构是形态学和背景评估的宝贵补充.
在结合建筑模式时,FNAC显示了甲状腺病变的高诊断潜力.

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