红细胞输血策略在心血管干预中
Melissa Foglietta1,2, Elena Bacigalupi1, Francesco Radico2
1Department of Neuroscience, Imaging and Clinical Sciences, University "G. d' Annunzio" Chieti-Pescara, 66100 Chieti, Italy.
Reviews in cardiovascular medicine
|August 14, 2024
概括
输血在心脏干预中很常见,但缺乏指导方针. 目前的保守策略旨在限制使用,但需要进一步研究以澄清输血影响.
科学领域:
- 心脏病学 心脏病学
- 输血医学 输血医学
- 心脏外科手术 心脏外科手术
背景情况:
- 在急性冠状动脉综合征,心脏手术和结构性干预过程中,异构红细胞输血经常被消耗.
- 在这些心脏病中,出血和贫血很普遍,需要输血.
- 目前的输血实践表现出广泛的变化,原因是数据有限和指南建议薄弱.
研究的目的:
- 要总结有关心脏干预中红细胞输血的当前文献.
- 批判性地分析支持心脏病患者输血策略的证据.
- 解决关于输血在心脏不良事件中的作用的不确定性.
主要方法:
- 对观察性和随机化研究的文献综述.
- 对输血策略现有证据的批判性分析 (自由与限制).
- 对心脏干预中输血影响的数据的检查.
主要成果:
- 观察性和随机研究表明,自由和受限制的红血输血策略的结果相似.
- 证据往往是有争议的和不确定的,有助于变化的临床实践.
- 输血在放大不良事件中的确切作用仍然不清楚.
结论:
- 目前青采用保守的血液输血方法,将血液的使用限制在拯救生命的情况中.
- 进一步的研究至关重要,以确定输血是否是不良事件的积极参与者或催化剂.
- 需要更明确的指导方针,以在心脏干预中进行最佳的红细胞输血管理.
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