低肌肉质量指数与拉丁美洲人口的2型糖尿病风险有关:一个横截面研究
Rosario Suárez1, Celina Andrade1, Estefania Bautista-Valarezo1
1School of Medicine, Universidad Técnica Particular del Loja, Loja, Ecuador.
Frontiers in nutrition
|August 14, 2024
概括
较高的肌肉质量与较低的2型糖尿病风险有关. 根据体重指数 (ASM/BMI) 调整的尾骨肌肉质量的评估可以帮助识别患糖尿病高风险的个体.
科学领域:
- 内分泌学 在内分泌学.
- 代谢健康 代谢健康
- 公共卫生 公共卫生
背景情况:
- 糖尿病带来了重大的健康挑战和并发症.
- 糖尿病风险存在预测得分,但肌肉质量与糖尿病风险之间的联系需要进一步调查.
- 胰岛素抵抗与肌肉质量有关,这表明它可能与糖尿病发展有关.
研究的目的:
- 研究肌肉质量与患2型糖尿病的风险之间的关系.
- 为了确定通过体重指数 (ASM/BMI) 调整的尾骨肌肉质量是否可以预测2型糖尿病风险.
主要方法:
- 一项涉及1388名员工的横截面研究.
- 使用FINDRISC评分来评估2型糖尿病的风险.
- 使用生物阻抗分析身体组成,重点是ASM/BMI.
- 使用后勤回归和ROC曲线分析来评估ASM/BMI的预测能力.
主要成果:
- 较高的ASM/BMI与两种性别的FINDRISC分数较低显著相关 (p < 0.001).
- 在将BMI从模型中排除后,ASM/BMI在男性 (p < 0.001) 和女性 (p < 0.001) 两种情况下都与糖尿病风险有显著的关联.
- 最佳的ASM/BMI切线值为0.82,显示了对2型糖尿病风险的适度预测能力 (AUC = 0.665).
结论:
- 评估肌肉质量,特别是ASM/BMI,可以帮助识别2型糖尿病高风险的成年人.
- 肌肉质量是量化男性和女性2型糖尿病风险的一个重要因素.
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