使用神经网络将遗传标记和作物模型参数联系起来,以增强整合性特征的基因组预测
Florian Larue1,2, Lauriane Rouan1,2, David Pot1,2
1Centre de Coopération Internationale en Recherche Agronomique pour le Développement (CIRAD), Unité Mixte de Recherche, Institut Amélioration Génétique et Adaptation des Plantes méditerranéennes et Tropicales (UMR AGAP), Montpellier, France.
Frontiers in plant science
|August 14, 2024
概括
卷积神经网络 (CNN) 通过捕捉复杂的遗传相互作用,准确地预测的产量. 将CNN与作物生长模型 (CGM) 结合起来,进一步提高了植物性能预测的准确性.
科学领域:
- 植物育种和遗传学
- 机器学习在农业中的应用
- 基因组预测 基因组预测
背景情况:
- 预测作物表现是复杂的,涉及遗传,环境和表观相互作用.
- 经典的基因组预测 (GP) 模型主要捕捉附加效应,限制它们模拟非附加相互作用的能力,如epistasis.
- 机器学习和深度学习为模拟这些复杂的非线性效应提供了潜力.
研究的目的:
- 评估卷积神经网络 (CNN) 与传统的GP方法来预测的地面新鲜重量.
- 评估将作物生长模型 (CGM) 与GP集成的实用性,以提高整合性特征的预测.
主要方法:
- 开发了一个卷积神经网络 (CNN),并与LASSO和贝叶斯C回归方法进行了比较.
- 土上空新鲜重量被用作预测的整合性质.
- 研究了一种混合方法,将CGM与GP结合起来.
主要成果:
- 与LASSO和Bayes C.相比,CNN显示出更高的预测准确度.
- 整合CGM与GP显著提高了所有测试的回归方法的预测能力.
- CNN更适合预测复杂的,整合性的植物特征.
结论:
- 非线性预测方法,特别是CNN,对于模拟植物中复杂的遗传结构是有效的.
- 将作物生长模型与基因组预测相结合,为改善作物性能预测提供了一个有希望的策略.
- 这些发现支持开发先进的基因组到表型模型.
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