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嗅觉障碍者和健康对照者的嗅觉感知指纹

Eva Drnovsek¹, Antje Haehner¹, Moustafa Bensafi²

¹Smell and Taste Clinic, Department of Otorhinolaryngology Technische Universität Dresden Dresden Germany.

Laryngoscope investigative otolaryngology

|August 14, 2024

概括

嗅觉感知指纹 (OPF) 是独立于特定的气味. 这些指纹有效地将嗅觉功能障碍患者与健康对照者区分开来,突出了嗅觉感知上的差异.

科学领域:

神经科学是一个神经科学.
感官科学感官科学
心理物理学的精神物理.

背景情况:

嗅觉感知指纹 (OPF) 使用气味描述器等级来描述个人的嗅觉感知.
之前的研究表明,OPF可以从对照者中区分COVID-19相关的嗅觉功能障碍 (OD),但使用了相同的气味剂.
OPFs的气味独立性及其区分OD与各种原因的能力仍需得到充分评估.

研究的目的:

重新分析已发表的数据集,以确认OPF的气味独立性.
评估OPF是否能够区分与对照组相比,不同病因的OD患者.
调查诊断和年龄对OPF的影响.

主要方法:

重新分析了一组数据集,其中包括104名对照和42名OD患者.
参与者使用感知描述符 (愉悦性,强度,熟悉性,可食性等) 评价每组10种气味. 通过计算机控制的嗅计.
统计分析包括对变异的多变量分析和随机森林分类.

主要成果:

对变异的多变量分析证实了OPF是独立于气味的.
诊断和年龄显著影响了OPF,分别解释了11%和5%的差异.
一个随机的森林分类器以80%的准确度根据OPF将患者与对照区分开来.

结论:

嗅觉感知指纹 (OPF) 是强大的,不依赖于特定的气味剂.
与对照组相比,嗅觉功能障碍患者认为气味不那么熟悉,不那么强烈,不那么食用.
OPFs提供了一个有价值的工具,用于区分由各种原因引起的嗅觉功能障碍.

关键词:

嗅觉嗅觉是一种嗅觉.嗅觉功能障碍嗅觉功能障碍嗅觉感知是一种嗅觉感知.嗅觉感知指纹的指纹气味味道味道味道味道

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