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Updated: Jun 17, 2025

Parallel Interrogation of β-Arrestin2 Recruitment for Ligand Screening on a GPCR-Wide Scale using PRESTO-Tango Assay
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设计和评估第一代异构功能PPARα/STING调节器的设计和评估

Bo Hu1, Yi Cui2,3, Julia J Lee1

  • 1Department of Medicinal Chemistry, College of Pharmacy, University of Minnesota, Minneapolis, Minnesota 55414, United States.

ACS medicinal chemistry letters
|August 14, 2024
PubMed
概括

这项研究介绍了BH400,一种针对PPARα和STING的新型双调制器,可以改善对糖尿病视网膜病变和与年龄相关的黄斑变性等炎症性视网膜疾病的保护.

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