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Updated: Jun 17, 2025

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无素HiBiT和NanoLuc标记系统作为监测向蛋白质降解的替代工具

Hanfeng Lin1,2, Kristin Riching3, May Poh Lai4

  • 1The Verna and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, Texas 77030, United States.

ACS medicinal chemistry letters
|August 14, 2024
PubMed
概括

新的无素融合标签,HiBiT-RR和nLucK0,在蛋白降解 (TPD) 研究中减少了人工物. 这些工具可确保更可靠地监测蛋白质降解,用于药物发现.

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