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Updated: Jun 17, 2025

Array Comparative Genomic Hybridization Array CGH for Detection of Genomic Copy Number Variants
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副本数的变化有助于严重出生缺陷的儿童恶性瘤的发展

Yichuan Liu1, Joseph Glessner1,2, Hui-Qi Qu1

  • 1Center for Applied Genomics (CAG), Children's Hospital of Philadelphia, PA, USA.

Molecular oncology
|August 14, 2024
PubMed
概括

患有出生缺陷 (BDs) 的儿童具有独特的遗传变化,拷贝数变异 (CNVs),这增加了他们患儿癌症的风险. 这项研究揭示了对这些儿童瘤发育机制的新见解.

关键词:
出生缺陷 产生的缺陷副本数量的变化 副本数量的变化儿科癌症 儿科癌症整个基因组测序的测序.

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