遗传学医疗保健提供者的经验咨询患者与消费者基因组测试的结果
Magan Trottier1, Dina Green1, Hannah Ovadia2
1Department of Medicine, Memorial Sloan Kettering Cancer Center, New York City, New York, USA.
Molecular genetics & genomic medicine
|August 14, 2024
概括
遗传学提供者报告说,在向消费者就基因组测试结果提供咨询方面存在重大挑战,许多人担心潜在的危害. 需要合作来解决与广泛的消费者基因组测试相关的风险.
科学领域:
- 基因组医学是基因组医学.
- 基因咨询 基因咨询
- 生物伦理学生物伦理学
背景情况:
- 消费者基因组测试 (CGT) 正在迅速扩大,监管监督最小.
- 评估医疗保健提供者对CGT的经验至关重要,因为它的流行率越来越高.
研究的目的:
- 评估遗传学医疗保健提供者的经验,为患者提供有关消费者基因组测试结果的咨询.
- 确定与CGT相关的挑战和感知到的利益/损害.
主要方法:
- 在139名遗传学医疗保健提供者中进行了回顾性调查.
- 受访者来自专业遗传学学会和实践社区.
主要成果:
- 41%的供应商认为CGT的危害超过了好处;38%的供应商尚未决定.
- 94%遇到咨询挑战,包括心理社会事件 (76%),不正确的变体解释 (68%) 和未经证实的结果 (69%).
- 较高的挑战分数与感知到的更大的伤害相关,而较高的CGT数量与感知到的更大的好处相关.
结论:
- 遗传学提供者在对CGT进行咨询时面临着重大的心理社会和医疗挑战.
- 加强监管机构,实验室,提供商和消费者之间的合作对于减轻CGT风险至关重要.
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