特拉斯图祖马布诱导的视神经炎:"失明"的副作用
1Dr Abdurrahman Yurtaslan Ankara Oncology Education and Research Hospital, Health Sciences University, Ankara, Turkey.
概括
乳腺癌治疗药物trastuzumab可以导致由于视神经炎引起的急性视力丧失. 早期检测和管理对于接受这种治疗的患者至关重要.
科学领域:
- 在瘤学瘤学.
- 眼科医生 眼科 眼科
- 药理学 药理学是指药理学的学科.
背景情况:
- 特拉斯图祖马布是一种向治疗,它改善了HER2阳性乳腺癌的治疗结果.
- 与trastuzumab治疗相关的不良事件需要仔细监测.
研究的目的:
- 报告一个用trastuzumab治疗的患者的视神经炎的次要严重视力丧失病例.
- 为了突出Trastuzumab诱导的视神经病变的潜力.
主要方法:
- 一份病例报告,一名60岁的女性患有HER2阳性乳腺癌,正在接受trastuzumab治疗.
- 记录了临床表现,诊断工作和视力丧失的治疗过程.
主要成果:
- 在开始辅助治疗后,患者经历了逐渐的视力丧失.
- 尽管用脉冲类固醇治疗和停止使用trastuzumab,视力敏度仍然严重受损.
结论:
- 特拉斯图祖马布诱导的视神经炎是一种罕见但严重的不良事件.
- 临床医生应警治疗trastuzumab的患者的视觉障碍,并考虑早期干预.
相关概念视频
Glaucoma: Overview
528
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
528
Photoreceptors and Visual Pathways
5.9K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
5.9K
Open Angle Glaucoma: Treatment
413
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
413
Angle Closure Glaucoma: Treatment
454
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
454


