右心室回声心电图功能参数的预测值,用于预发性肺高血压中的死亡率预测:系统性审查和元分析
Bryan Gervais de Liyis1, Luh Oliva Saraswati Suastika2, Jane Carissa Sutedja1
1Faculty of Medicine, Universitas Udayana, Prof. I.G.N.G Ngoerah General Hospital, Denpasar, Bali, Indonesia.
概括
像TAPSE,RVLS,RVFAC,RVEF和RIMP这样的心声学参数可以预测毛囊前肺高血压 (PH) 中的死亡率. 这些右心室功能指标在患者结果中显示出显著的预后价值.
科学领域:
- 心脏病学 心脏病学
- 肺部医学 肺部医学
- 医疗成像医学成像
背景情况:
- 使用心声回声仪预后性指标对前毛囊性肺高血压 (PH) 死亡率的预后指标仍然没有确定性.
- 右心室 (RV) 功能障碍是PH进展和死亡的一个关键因素.
研究的目的:
- 评估各种右心室回声心脏图功能参数的预后价值,以预测患有毛囊前肺高血压的患者的死亡率.
主要方法:
- 在ScienceDirect,Medline和Cochrane数据库中进行了系统的文献搜索,以进行纵向研究.
- 对三 annular 平面 缩 运动 (TAPSE),右心室 缩 压力 (RVSP),右心室 纵向 应变 (RVLS),右心室 分数面积变化 (RVFAC),右心室射出 分数 (RVEF) 和右心室心肌性能指数 (RIMP) 的危险比率 (HRs) 的元分析.
主要成果:
- 分析包括24项队列研究,共2171名参与者.
- TAPSE (HR: 1.28),RVLS (HR: 1.74),RVFAC (HR: 1.40),RVEF (HR: 1.08) 和RIMP (HR: 1.51) 是毛囊前PH死亡率 (p < 0.01) 的重要预测因素.
- RVSP没有显著的预后值 (HR:1.04,p = 0.14).
结论:
- 包括TAPSE,RVLS,RVFAC,RVEF和RIMP在内的心声学参数显示出显著的希望,作为毛囊前PH死亡率的预后指标.
- 这些功能性RV参数可以帮助对PH患者的风险分层和管理.
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