在需要长期雄激素剥夺治疗的前列腺癌男性中实施骨折风险评估:使用i-PARIHS实施框架进行系统范围审查
Qizhi Huang1, Caroline Mitchell2, Elisavet Theodoulou3
1Population Health, School of Medicine and Population Health, University of Sheffield, Sheffield, UK. q.huang@sheffield.ac.uk.
Journal of cancer survivorship : research and practice
|August 14, 2024
概括
接受抗雄激素缺乏治疗的前列腺癌男性面临骨折风险增加. 本综述确定了改善骨质疏松症护理和骨健康管理的障碍和策略.
科学领域:
- 在瘤学瘤学.
- 老年学是指老年学的学科.
- 公共卫生 公共卫生
背景情况:
- 抗雄激素剥夺疗法 (ADT) 对于前列腺癌 (PCa) 治疗至关重要.
- 在男性中,ADT增加骨质疏松症和脆弱性骨折的风险.
- 目前关于减轻骨折风险的指导方针未得到充分实施,导致骨质疏松症的诊断和治疗不足.
研究的目的:
- 综合关于在接受ADT (PCa-ADT) 的PCa男性中实施骨折风险降低指南的知识.
- 为医疗服务干预提供信息,旨在减少这一患者群体中骨折风险.
主要方法:
- 2000年1月至2023年1月期间发表的研究范围审查.
- 在四个数据库和额外的文献中进行搜索.
- 以i-PARIHS实施框架为指导的叙事综合.
主要成果:
- 九项研究符合纳入标准,在骨折风险评估中呈现出不同程度的改善.
- 关键障碍包括缺乏知识 (患者和临床医生),时间限制和组织问题.
- 有效的策略包括教育,多学科护理,综合工具和专业诊所.
结论:
- 在接受ADT的PCa男性中,对基于证据的骨医疗保健有显著的未满足需求.
- 本综述强调了在PCa-ADT患者中实施骨折风险评估的关键障碍和有效策略.
- 初级保健在治疗诱导的骨损失的管理中起着至关重要的作用;未来的服务重新设计应该涉及所有利益相关者.
相关概念视频
Disorders of the Male Reproductive System
367
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
367
Cancer Survival Analysis
334
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
334


