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Intracellular Phosphoflow Cytometry of Acute Myeloid Leukemia Patient-Derived Xenotransplants
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mTORC1对LST2进行酸化和稳定,从而对EGFR产生负调节

Stefania Battaglioni1, Louise-Marie Craigie1, Sofia Filippini1

  • 1Biozentrum, University of Basel, Basel 4056, Switzerland.

Proceedings of the National Academy of Sciences of the United States of America
|August 14, 2024
PubMed
概括

拉巴胺复合体1 (TORC1) 的位直接化LST2,这是一个调节表皮生长因子受体 (EGFR) 信号的蛋白质. 这种相互作用揭示了一个新的负反循环,其中mTORC1通过LST2.2.抑制EGFR信号传递.

关键词:
在LST2中,LST2是LST2.在TOS中,TOS的动画是TOS的动画.在mTOR信号传输中.负面的反是负面的反.酸化基质的酸化基质

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