为了确定中度至高级玻璃眼中中央视野进展的风险因素
Trupti S Patil1, Viswanathan Natarajan, Ronnie George
1Smt. Jadhavbai Nathamal Singhvi Glaucoma Services, Sankara Nethralaya Medical Research Foundation, Chennai, Tamil Nadu, India.
Indian journal of ophthalmology
|August 14, 2024
概括
平均偏差和基线损伤的变化速度预测了青光眼患者的中央视野进展. 了解这些风险因素有助于管理晚期玻璃眼.
科学领域:
- 眼科医生 眼科 眼科
- 视觉神经科学是一种神经科学.
背景情况:
- 玻璃眼是导致不可逆转失明的主要原因.
- 中央视野损失显著影响患者的生活质量.
- 确定进展的风险因素对于及时干预至关重要.
研究的目的:
- 为了确定与中度至高级初级开角青光眼中中央视野进展相关的风险因素.
- 用汉弗雷视野 (HVF) 10-2测试来分析点向上的进展.
主要方法:
- 包括中度至晚期原发性青光瘤患者和至少2年的随访5+可靠的HVF10-2测试.
- 用点wise线性回归 (PLR) 计算每个值位置的回归斜率.
- 定义进展为恶化的斜率> -1dB/年 (P<0.01) 或负的10-2平均偏差 (MD) 斜率 (P<0.05).
主要成果:
- 分析了74名患者的96只眼睛,随访时间中位数为4年.
- 28%的眼睛 (27/96) 根据10-2 PLR显示进展.
- 10-2MD变化率和基线24-2MD是进展的显著风险因素.
结论:
- 10-2平均偏差的变化率是点wise进展的关键预测指标.
- 基线视野损伤,包括24-2平均偏差和视野指数,也预测了进展.
- 这些发现强调了监测格洛科马管理中的变化速度和损伤严重程度的重要性.
更多相关视频
07:12Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss
Published on: April 11, 2025
308
08:55Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments
Published on: April 24, 2020
3.0K
相关概念视频
Glaucoma: Overview
528
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
528
Photoreceptors and Visual Pathways
5.9K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
5.9K
Open Angle Glaucoma: Treatment
413
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
413
Angle Closure Glaucoma: Treatment
454
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
454
