新血管格朗瘤手术治疗的长期结果:一项回顾性多中心研究
Julie Pegu1, Prerna Garg1, Rakesh Shakya2
1Department of Glaucoma and Anterior Segment, Glaucoma Services, Dr. Shroff's Charity Eye Hospital, New Delhi, India.
Indian journal of ophthalmology
|August 14, 2024
概括
垂眼切除术,青光眼排水装置和TSCPC为新血管青光眼提供类似的眼内压力控制. 带切除术可以改善视力,但并发症更多.
科学领域:
- 眼科医生 眼科 眼科
- 玻璃眼研究研究 玻璃眼研究
- 手术干预 手术干预
背景情况:
- 在眼内压力 (IOP) 管理方面,神经血管内光眼 (NVG) 构成了重大挑战.
- 对于晚期NVG病例而言,手术干预至关重要,NVG病例对医学治疗没有反应.
研究的目的:
- 为了比较手术结局的trabeculectomy (Trab),青光眼排水装置 (GDD) 植入,和跨囊环光凝血 (TSCPC) 在新血管青光眼患者.
- 评估每种手术方法的内视压缩,药物使用,视力敏度和并发症率.
主要方法:
- 2017年至2021年间在印度四个中心进行手术治疗的176例新血管性玻璃眼病患者的回顾性分析.
- 外科手术包括使用mitomycin-C (80只眼睛),GDD植入 (25只眼睛) 和TSCPC (71只眼睛) 的轨道切除术.
- 关键的结果指标是内皮压的降低,抗白内障药物 (AGM) 的使用,最佳校正的视力敏度 (BCVA) 和并发症发生率.
主要成果:
- 所有手术组都在术后实现了显著的内皮压降低.
- 一年完整的成功率:Trab (54.3%),GDD (42.9%),TSCPC (33.3%).这些研究的成功率是什么? 有资格的成功率:Trab (36.7%),GDD (57.1%),TSCPC (58.9%). 这是一个很好的例子.
- 与GDD (0.11 LogMAR) 和TSCPC (-0.35 LogMAR) 相比,轨道切除术显示出优异的视觉结果改善 (0.24 LogMAR). 并发症:Trab (27%),TSCPC (14%),GDD高血压阶段 (40%).
结论:
- 轨道切除术,GDD和TSCPC在控制新血管玻璃眼中的IOP方面是有效的.
- 青光眼排水装置与更高的药物依赖性有关.
- 带切除术提供了更好的视觉结果,但需要仔细管理其更高的并发症风险,强调需要个性化治疗策略.
相关概念视频
01:25Glaucoma: Overview
528
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
528
01:28Angle Closure Glaucoma: Treatment
454
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
454
01:27Open Angle Glaucoma: Treatment
413
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
413