超越神经元的电信号传输
Travis Monk1, Nik Dennler2,3, Nicholas Ralph4
1International Centre for Neuromorphic Systems, MARCS Institute, Western Sydney University, Sydney, NSW 2747, Australia travis.monk@westernsydney.edu.au.
Neural computation
|August 14, 2024
概括
非神经生物体使用电信号来刺激反应,为神经动作潜能 (AP) 提供了洞察力. 将这些简单的系统进行比较,可以发现神经元是如何进化为复杂环境的速度和灵敏性的.
科学领域:
- 理论神经科学理论神经科学
- 比较生理学比较生理学
- 细胞电生理学 细胞电生理学
背景情况:
- 神经动作潜能 (AP) 是复杂的,很难被解释为信号编码器.
- 更简单的,没有神经元的生物也使用电脉冲来转换刺激并影响行为.
研究的目的:
- 研究不同生命形式的非神经刺激转导.
- 为了比较非神经电信号与神经AP的属性.
- 推断神经元的进化压力和功能作用.
主要方法:
- 对细菌,原生动物,植物,真菌和没有神经元的动物中非神经刺激转导的现有文献的综述.
- 分析电信号属性:振幅,持续时间,离子基础,耐火周期和生态功能.
- 对非神经和神经电信号的比较分析.
主要成果:
- 非神经生物将环境刺激转化为电信号,从而改变行为.
- 非神经信号具有很高的灵敏度和特异性,但通常比神经AP慢.
- 神经元似乎以速度和灵敏度来交易特异性,这可能是由时间压力驱动的.
结论:
- 细胞刺激转导作为检测到的环境事件的时间标记.
- 神经AP可以被视为快速的,虽然杂的检测断言.
- 神经系统在时间限制下优先检测弱信号,可能是通过神经元中的概率计算.
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