下肢肌肉的剪切模块在有轻度低血压的学龄儿童中
Miran Goo1, Leanne M Johnston2, Kylie Tucker1
1The University of Queensland, School of Biomedical Sciences, Brisbane, Australia.
Journal of biomechanics
|August 14, 2024
概括
患有轻度低血压症的儿童与患有脑或杜申肌肉衰竭的儿童相比,表现出较低的肌肉剪切模量. 肌肉硬性随着肌肉长度增加而增加,在低压儿童中.
科学领域:
- 生物医学工程 生物医学工程
- 肌肉骨生理学 肌肉骨生理学
- 儿科康复儿童康复中心
背景情况:
- 儿童的低血压与改变的肌肉特性有关.
- 了解肌肉剪切模量对于评估儿科患者的肌肉功能至关重要.
- 以前的研究还没有完全描述不同肌肉长度的低压儿童的剪切模量.
研究的目的:
- 为了比较下肢肌肉剪切模块在轻度低血压的儿童与典型发育 (TD) 的儿童和那些有其他发育障碍的儿童.
- 为了研究肌肉剪切模量和肌肉长度 (净纵向张力角 - 净LTA) 之间的关系,在低压儿童.
- 在这个队列中检查剪切模和年龄,性别和体重指数 (BMI) 之间的相关性.
主要方法:
- 剪切波弹性成像被用来测量19名轻度低血压的儿童的直骨,双腿 (BF),前 (TA) 和腹半 (GL) 的静止剪切模量.
- 肌肉剪切模量被评估在短和长的肌肉长度,定义通过Net-LTA.
- 数据与TD儿童的现有数据和发展障碍儿童的范围审查进行了比较.
主要成果:
- 切割模量在较长的肌肉长度明显高于较短的肌肉长度在所有四个测量肌肉在低压儿童 (p <0.01).
- 剪切模量与年龄 (BF-short,GL-short) 和BMI (BF-short) 有关.
- 轻度低血压症儿童的剪切模值值低于杜申肌肉发育不良和脑的儿童,但不是TD儿童.
结论:
- 轻度低血压症儿童的肌肉剪切模块随着肌肉长度增加 (净LTA更高) 增加.
- 轻度低垂体症的特征是较低的肌肉剪切模量,相比于更严重的疾病,如脑麻和杜申肌肉发育不良.
- 这些发现有助于理解低血压儿科患者群体的生物力学差异.
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