经更年期妇女长期COVID综合征的危险因素,此前已报告COVID-19的诊断
Marian L Neuhouser1, Hamza Islam Butt2, Chengcheng Hu2
1Cancer Prevention Program, Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, United States.
识别长期COVID的危险因素至关重要. 经历体重减轻,移动性问题和某些健康状况的老年女性在感染SARS-CoV-2后更有可能发展长期COVID.
科学领域:
- 老年学是指老年学的学科.
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 长期COVID综合征影响10-20%的SARS-CoV-2感染后个体,症状持续超过8周.
- 长期COVID的风险因素仍然不明,特别是在面临更高COVID-19并发症风险的老年人群中.
研究的目的:
- 确定与绝经后妇女长期COVID发展相关的关键风险因素.
- 调查先前存在的健康状况和长期COVID发展之间的关系.
主要方法:
- 利用了来自妇女健康倡议 (WHI) 队列的数据,包括绝经后妇女.
- 采用机器学习,从几十年来收集的人口和健康数据中确定前20个风险因素.
- 使用标准共识标准对长期COVID进行分类,并通过后勤回归分析风险因素.
主要成果:
- 在37,280名受访者中,1237人报告COVID-19检测结果呈阳性,其中425人 (30%) 患有长期COVID.
- 常见的长期COVID症状包括神经,心肺,肌肉骨问题,疲劳和不适.
- 确定的风险因素,如体重减轻,身体/运动限制,以及特殊情况,如类风湿性关节炎和心脏门手术史.
结论:
- 了解长期COVID风险因素是阐明这种疾病复杂病因的关键初步步骤.
- 研究结果强调了特定的人口和健康指标,这些指标可以预测老年女性的长期COVID发展.
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