基于汗水的压力选使用气色谱-离子运动谱和电子鼻子
Nuttanee Tungkijanansin1, Patthrarawalai Sirinara2, Chavit Tunvirachaisakul3
1Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok, 10330, Thailand.
Analytica chimica acta
|August 14, 2024
概括
这项研究引入了一种使用汗液中的挥发性化合物进行压力查的新,非侵入性方法. 气色谱-离子移动谱和电子鼻子技术可快速准确地检测护士的高压力水平.
科学领域:
- 分析化学 分析化学
- 生物技术是生物技术.
- 精神病学是一个精神病学.
背景情况:
- 传统的压力诊断方法,如问卷,可能会产生偏见.
- 精神病学家的观察是准确的,但耗时且无法扩展.
- 这项研究探讨了新的,快速的,非侵入性的压力查方法.
研究的目的:
- 建立压力查的替代性,快速和非侵入性方法.
- 为了利用气色谱-离子移动谱 (GC-IMS) 和电子鼻子 (e-nose) 进行应力检测.
- 在汗水中识别挥发性化合物标记物,表明高压力水平.
主要方法:
- 收集了154名女护士的下汗液样本.
- 使用GC-IMS分析汗液样本以识别挥发性化合物.
- 采用部分最小平方差分分析和接收器运行特征曲线进行数据分析.
- 使用电子鼻子传感器进行高压力病例查.
主要成果:
- 在汗水中确定了潜在的压力标志物:氨,乙,甲醇,八,五,和二甲基胺.
- 在GC-IMS分析中,准确度达到了87%,灵敏度达到了86%,选择性达到了88%.
- 电子鼻子查在识别高压力病例方面表现出89%的准确性.
- 与GC-IMS标记器峰值数据相关联的电子鼻子传感器响应.
结论:
- 这是第一次研究出汗中的挥发性化合物标记物用于高压力查的研究.
- 开发的GC-IMS和e-nose方法是简单的,可靠的,快速的和非侵入性的.
- 这些方法可以适应便携式电子鼻子平台,用于实际的压力查应用,特别是护士.
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