使用高频超声波对表皮质Rete Peg变异的相关性进行研究
Ankita Samal1, Hsun-Liang Chan2, I-Ching Wang3
1Department of Radiology, Michigan Medicine, University of Michigan, Ann Arbor, MI, USA; Department of Periodontology, University of Iowa College of Dentistry and Dental Clinics, Iowa City, IA, USA.
Ultrasound in medicine & biology
|August 14, 2024
概括
高频超声波可以测量口腔上皮层和网尺寸,与组织学相关联. 这种非侵入性成像可能有助于早期检测口腔病理和评估伤口愈合.
科学领域:
- 口腔生物学和组织学.
- 医学成像医学成像
- 临床前研究 临床前研究
背景情况:
- 重复钉子,口腔上皮的投影,在病理条件下改变尺寸.
- 这些变化可能表明伤口愈合状态.
- 非侵入性,高频超声波 (US) 可以检测这些组织病理变化.
研究的目的:
- 在临床前模型中将超声波图像与组织学相关联.
- 用US.来量化不同牙部位的上皮层和网尺寸.
主要方法:
- 从小猪口腔软组织中获得了形B模式超声波图像.
- 组织学样本被染色,数字化,并用美国图像进行注册.
- 手动注释测量了表皮和网尺寸 (D1和D2) 用于统计分析.
主要成果:
- 超声波测量显示,D1的平均偏差为-0.64微米,D2的平均偏差为-12微米.
- D1的方差系数为55%,D2的方差系数为39%.
- 超声波和组织学都表现出类似的能力,在牙位置上区分上皮层.
结论:
- 用临床成像硬件评估亚毫米软组织尺寸是一个不断发展的领域.
- 未来的研究可能能够诊断口腔病理和异常的伤口愈合.
- 这项技术可能会减少假阳性活检指示.
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