功能性结果和喉切除术全腔切除术后的存活率:一个系统性审查
A M Weyh1, C Mosquera2, S Nedrud3
1Department of Oral and Maxillofacial Surgery, University of Illinois Chicago, Chicago, IL, USA.
International journal of oral and maxillofacial surgery
|August 14, 2024
概括
带喉切除术 (TGL) 的全腔切除术提供了有限的功能性言语和吞恢复. 高复发率强调了需要仔细选择患者进行这种广泛的癌症手术.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 头部和部手术 头部和部手术
背景情况:
- 带喉切除术全腔切除术 (TGL) 是一种针对晚期舌头和喉癌的激进手术.
- 这种手术带有重大风险,并严重影响生活质量,包括言语和吞功能.
研究的目的:
- 在接受TGL的患者中,系统地审查和量化功能结果和生存率.
- 评估TGL的瘤疗效和对生活质量的影响.
主要方法:
- 根据PRISMA指南进行了系统审查.
- 文献搜索确定了748项研究;七项符合分析的纳入标准.
主要成果:
- 只有12.1%的患者在TGL后实现了功能性语音;语音康复数据稀少.
- 53.3%的人恢复了吞能力,但37.7%的人仍然依赖胃口管.
- 一年复发率为52%,无病生存率为48%.
结论:
- TGL与发言和吞功能恢复不佳有关.
- 高的早期复发率挑战了癌症益处与生活质量之间的权衡.
- 在经过彻底的风险-益处讨论后,TGL应保留给精选的患者.
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