快速进食速度与代谢功能障碍相关的脂肪性肝病之间的关联:一个多中心横截面研究和元分析
Miao Zhang1,2, Xiaoyang Sun1,2, Xiaopeng Zhu1,2
1Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai, China.
Nutrition & diabetes
|August 14, 2024
概括
快速饮食,定义为五分钟以下的餐,与更高的代谢功能障碍相关的脂肪性肝病 (MASLD) 风险有关. 这一发现突出了与现代饮食习惯相关的潜在公共卫生问题.
科学领域:
- 代谢健康 代谢健康
- 胃肠病学 胃肠病学
- 公共卫生 公共卫生
背景情况:
- 现代生活方式往往缩短了饮食时间.
- 关于快速进食与代谢疾病之间的联系的研究有限.
研究的目的:
- 调查快速进食与代谢功能障碍相关的脂肪性肝病 (MASLD) 之间的联系.
- 通过元分析,将当前研究数据与先前的研究结合起来.
主要方法:
- 一项针对1965年中国参与者的多中心横截面研究.
- 快餐定义为<5分钟的餐时间;按频率分类 (≤1/月,≤1/周,≥2/周).
- 五项研究的元分析,包括目前的一项研究.
主要成果:
- 经常吃快饭的人 (≥2/周) 的MASLD患病率为59.3%,不经常吃快饭的人 (≤1/月) 的患病率为46.2%.
- 快餐的频率独立预测了MASLD风险 (OR,1.29).
- 频繁的快餐显示,患MASLD的风险增加了81%;元分析证实了这一关联 (合并OR,1.22).
结论:
- 频繁的快餐与患MASLD的风险增加有关.
- 这种关联甚至在调整多个混因素后也保持不变.
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