相关实验视频
Updated: Jun 17, 2025

07:52
In Vivo Wireless Optogenetic Control of Skilled Motor Behavior
Published on: November 22, 2021
3.3K
运动皮层中旋转动态的取决于范围的重定位
David A Sabatini1,2, Matthew T Kaufman3,4
1Department of Organismal Biology and Anatomy, The University of Chicago, Chicago, IL, 60637, USA.
Nature communications
|August 14, 2024
概括
在达到时的运动皮质神经活动展示了取决于位置的旋转,一种新的模型解释了复杂的动力学,并改进了运动解码. 这促进了对神经群体活动和运动控制的理解.
科学领域:
- 神经科学是一个神经科学.
- 发动机控制器的控制器
- 计算神经科学是一种神经科学.
背景情况:
- 运动皮层中的神经元在达到运动时显示复杂的活动模式.
- 虽然单个神经元的活动与运动参数相关,但它只能部分解释神经反应,这表明人口层面的动态是至关重要的.
- 之前的模型将这些动态描述为"旋转",神经活动在状态空间中运行.
研究的目的:
- 为了研究运动皮层神经动力学的新特性,在达到标准模型无法解释的过程中.
- 开发和验证一个新的模型",位置依赖旋转",以更好地捕捉神经活动.
- 探索神经表达与运动皮层控制中的动态之间的关系.
主要方法:
- 重新分析了来自雄性 rhesus 的数据集.
- 开发了"取决于位置的旋转"模型.
- 从神经增数据中解码到达动力学.
主要成果:
- 确定了两个标准动力学无法解释的关键特征:不同范围的不同旋转平面和与状态空间中的活动位置相关的平面变化.
- "位置依赖旋转"模型成功地适应了几乎所有的运动皮质活动在达到.
- 达到动力学的高质量解码显示了与尖端活动的准线性关系.
结论:
- "取决于位置的旋转"模型提供了比以前的模型更全面的解释运动皮质活动在达到.
- 不同的旋转平面可以实现更丰富的运动输出,增强运动皮层的能力.
- 该研究整合了表示和动态概念,展示了状态空间位置 (表示) 如何通过动态转换为时间变化的命令信号.
相关概念视频
Motor and Sensory Areas of the Cortex
3.6K
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
3.6K
Somatosensory, Motor, and Association Cortex
453
The somatosensory cortex in the parietal lobes is crucial for interpreting sensory data such as touch, temperature, and proprioception. The somatosensory cortex, situated in the parietal lobes, plays a vital role in interpreting sensory information like touch, temperature, and proprioception—awareness of body position. This specialized brain region features an organized structure wherein neurons at the top primarily process sensations originating from the lower body. In contrast, those at...
453
Indirect Motor Pathways
1.5K
The indirect motor or extrapyramidal pathways originate in the brainstem, the lower portion of the brain that connects it to the spinal cord. They consist of several distinct tracts, each with specialized functions. The four main tracts of the indirect motor pathways are the vestibulospinal tract, the reticulospinal tract, the tectospinal tract, and the rubrospinal tract.
The vestibulospinal tract originates in the vestibular nuclei of the brainstem. The vestibular system detects changes in...
The vestibulospinal tract originates in the vestibular nuclei of the brainstem. The vestibular system detects changes in...
1.5K
Rotational Motion about a Fixed Axis
445
A rigid body's rotation around a fixed axis makes every point within it trace a circular path around a specific line or point. The term given to this type of spinning is defined by the angular position, symbolized by the angle θ. This angle is gauged from a static reference line to the revolving object. From this angular position, any variation is referred to as angular displacement, denoted by dθ. The extent of this displacement can be calculated in degrees, radians, or...
445
Relative Motion Analysis using Rotating Axes-Problem Solving
394
Consider a crane whose telescopic boom rotates with an angular velocity of 0.04 rad/s and angular acceleration of 0.02 rad/s2. Along with the rotation, the boom also extends linearly with a uniform speed of 5 m/s. The extension of the boom is measured at point D, which is measured with respect to the fixed point C on the other end of the boom. For the given instant, the distance between points C and D is 60 meters.
Here, in order to determine the magnitude of velocity and acceleration for point...
Here, in order to determine the magnitude of velocity and acceleration for point...
394
Somatosensation
36.5K
The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
36.5K

