戒烟对内皮功能的影响,通过流介导总扩张来评估
Naoki Okuyama1, Kazuo Fukumoto2, Yasuhiko Takemoto1,3
1Department of Medical Education and General Practice, Osaka Metropolitan University Graduate School of Medicine, 1-4-3 Asahi-machi Abeno-ku, Osaka, 545-8585, Japan.
Cardiovascular ultrasound
|August 14, 2024
概括
戒烟改善了内皮功能,特别是流媒总扩张 (FMTD). 这种改善在女性和吸烟者中更为明显,这表明口肺炎有助于风险分层.
科学领域:
- 心血管研究研究心血管研究
- 内皮功能研究 研究内皮功能研究.
- 戒烟的研究 戒烟的研究
背景情况:
- 低流介导收缩 (L-FMC) 提供了超出流介导扩张 (FMD) 的内皮功能的见解.
- 流介总扩张 (FMTD),包括L-FMC,是内皮功能报告不足的指数.
- 评估戒烟对口病和口肺炎的影响对于了解心血管健康至关重要.
研究的目的:
- 评估戒烟对内皮功能的影响,使用口病和口肺炎.
- 确定影响戒烟后内皮功能改善的临床因素.
主要方法:
- 118名没有先前冠状动脉疾病的吸烟者接受了戒烟治疗.
- 在治疗前和20周后测量了内皮功能 (%FMD, %L-FMC, %FMTD).
- 多变量线性回归分析了戒烟效应和与基线变量相互作用.
主要成果:
- 戒烟与%FMTD的显著改善有关 (p=0.024).
- 与男性相比,女性的FMTD%的改善显著更大 (p<0.001).
- 在每天吸烟较少的香烟 (p=0.042) 和较小的基线光线直径 (p=0.023) 的个体中观察到更大的%FMTD改善.
结论:
- 戒烟对内皮功能有积极的影响,正如FMTD改善所表明的那样.
- 性别,吸烟强度和基线血管直径是调节 FMTD 停止后改善的重要因素.
- FMTD显示出作为在戒烟过程中进行风险分层的工具的潜力.
相关概念视频
01:30Assessment of Airway, Skin Color, and Use of Accessory Muscles
A thorough assessment of respiratory health is paramount in clinical settings to identify and manage respiratory distress and ensure adequate oxygenation. This article elaborates on the critical aspects of respiratory evaluation, including airway assessment, skin color examination, and the observation of accessory muscle use, which are integral to effectively diagnosing and managing patients with respiratory conditions.
Introduction
The initial evaluation of a patient's respiratory system...
Introduction
The initial evaluation of a patient's respiratory system...
01:23Drugs Acting on Autonomic Ganglia: Stimulants
Ganglionic stimulants activate NM nicotinic receptors in autonomic ganglia, falling into two categories: nicotine mimetics [e.g., lobeline, dimethylpiperazine, tetramethylammonium] and muscarinic receptor agonists [e.g., muscarine, methacholine]. The first category's action is rapid and blocked by nicotinic receptor antagonists, while the second category's action is delayed and blocked by atropine-like agents. Nicotine, an alkaloid, affects the heart rate by stimulating sympathetic or...
01:24Pressure Relationships in Thoracic Cavity
Breathing, otherwise known as pulmonary ventilation, is the process of air movement into and out of the lungs. The main mechanisms propelling pulmonary ventilation are atmospheric pressure (Patm), intra-pulmonary (Ppul ) or intra-alveolar pressure (Palv) within the alveoli, and intrapleural pressure (Pip) within the pleural cavity.
Breathing Mechanisms
Both intra-alveolar and intrapleural pressures rely on specific lung properties. The ability to breathe—allowing air to enter the lungs during...
Breathing Mechanisms
Both intra-alveolar and intrapleural pressures rely on specific lung properties. The ability to breathe—allowing air to enter the lungs during...
01:19Factors Affecting Pulmonary Ventilation
Besides the pressure difference between the external environment and the lungs, the airflow rate and ease of pulmonary ventilation are also influenced by three other factors: surface tension of the fluid in the alveoli, compliance of the lungs, and airway resistance.
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
01:24Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features
Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...