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Immunometabolic Circuits in Infection for Advancing Host Directed Therapies
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激活cGAS/STING以驱动抗癌免疫的免疫代谢途径

Francisca Borges1, Abhishek D Garg1

  • 1Cell Stress and Immunity (CSI) Laboratory, Department for Cellular and Molecular Medicine (CMM), KU Leuven, Leuven, Belgium.

Cancer research
|August 15, 2024
PubMed
概括

血清素缺乏会触发cGAS/STING通路,增强抗瘤免疫力. 这种代谢策略在癌症治疗方面表现有前途,在与PD1阻断相结合时,增强免疫反应和改善患者存活率.

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