用纳米疗法向癌细胞的纳米材料:向响应性系统过渡
Bhawana Jain1, Dakeshwar Kumar Verma2, Reena Negi Rawat3
1Siddhachalam Laboratory, Institute of Life Science Research, Raipur, Chhattisgarh, 493221, India.
Current pharmaceutical design
|August 15, 2024
概括
纳米材料通过克服化疗的局限性,提供了有前途的癌症治疗方法. 需要进一步的研究来克服这些纳米药物的临床转化障碍.
科学领域:
- 在瘤学瘤学.
- 纳米技术纳米技术
- 材料科学 材料科学 材料科学
背景情况:
- 目前的化疗面临的挑战包括细胞毒性,缺乏选择性和多药耐药性.
- 纳米材料 (1-100纳米) 具有适用于癌症治疗的特性,包括细胞毒性和药物输送能力.
- 尽管进行了广泛的研究,但纳米药在临床转化中面临着重大障碍.
研究的目的:
- 审查用于癌症治疗的新型纳米材料.
- 确定纳米药物的临床研究的障碍.
- 探索纳米材料在癌症治疗和治疗术中的有效应用策略.
主要方法:
- 最近用于癌症治疗的纳米材料的文献综述.
- 分析纳米药物临床转化中的挑战.
- 纳米载体的概述,准策略和神经应用.
主要成果:
- 纳米材料显示出克服传统化疗局限性的潜力.
- 一些纳米载体和向策略正在探索特定的瘤向.
- 基于纳米技术的治疗术在癌症检测和治疗方面取得了进展.
结论:
- 纳米材料在推进癌症治疗和神经科学方面具有重大前景.
- 解决临床转化障碍对于实现纳米药物的全部潜力至关重要.
- 进一步的研究是必要的,以弥合实验室发现和临床应用之间的差距.
相关概念视频
Targeted Cancer Therapies
7.5K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.5K
Combination Therapies and Personalized Medicine
4.9K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
4.9K
Tumor Immunotherapy
493
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
493


