用对比度增强的超声波甲状腺成像报告和数据系统对良性和恶性甲状腺结节的分类数据的诊断效果
Yu-Ping Yang1, Guo-Li Zhang1, Hong-Lian Zhou1
1Department of Ultrasound, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Quantitative imaging in medicine and surgery
|August 15, 2024
概括
与对比增强的超声波甲状腺成像报告和数据系统 (CEUS TI-RADS) 能够有效地区分良性和恶性甲状腺结节. 它在1-4厘米之间的结节中表现最好,显示出高的诊断准确性和良好的观察者间协议.
科学领域:
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
- 内分泌学 在内分泌学.
背景情况:
- 对比增强的超声波甲状腺成像报告和数据系统 (CEUS TI-RADS) 是甲状腺结节的第一个国际风险分层系统.
- 它集成了传统的超声波 (US) 和对比增强超声波 (CEUS) 以提高诊断能力.
- 评估其诊断疗效和观察者间的共识对于临床应用至关重要.
研究的目的:
- 评估CEUS TI-RADS在区分良性和恶性甲状腺结节的诊断性能.
- 评估CEUS TI-RADS分类系统的观察者间协议.
- 分析CEUS TI-RADS在不同甲状腺结节大小组的疗效.
主要方法:
- 通过使用US和CEUS诊断的433名患者的467个甲状腺结节的回顾性分析.
- 基于US和CEUS特征的CEUS TI-RADS分类,结节按大小分类 (≤1厘米,>1-4厘米,>4厘米).
- 风险因素的后勤回归,诊断有效性 (AUC) 的ROC分析,以及观察者间协议的ICC.
主要成果:
- 在诊断恶性结节时,CEUS TI-RADS的整体AUC为0.898.
- 诊断效率因大小而异,在1~4厘米 (B组) 的结节中,AUC (0.949) 是最高的.
- 在B组中观察到高灵敏度 (95.9%),特异性 (88.1%) 和准确性 (92.8%),观察者之间的一致性很好 (ICC=0.862).
结论:
- CEUS TI-RADS在区分甲状腺结节方面是有效的,对于尺寸为1-4厘米的结节具有最佳性能.
- 恶性瘤的独立风险因素包括点状回声发作焦点,高于宽的形状,甲状腺外侵袭,不规则的边缘,低声度和低声增强.
- 该系统显示出显著的临床实用性和可靠的观察者间协议,用于甲状腺结节风险分层.
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