在孤立的完整右捆分支区块与左捆分支区块之间,机械失调导致的心室功能障碍
Mengjia Chen1,2, Xueyang Zhang1,2, Guangyuan Li1,2
1Department of Cardiovascular Ultrasound, The First Hospital of China Medical University, Shenyang, China.
Quantitative imaging in medicine and surgery
|August 15, 2024
概括
隔离完整的右束支部阻断 (CRBBB) 损害心脏同步和功能,结果比CLBBB更差. 右心室同步与RV缩功能障碍有关,突出显示了CRBBB患者需要心声图评估和监测的必要性.
科学领域:
- 心脏病学 心脏病学
- 心脏电生理学 心脏电生理学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
背景情况:
- 没有结构性心脏病的孤立完整捆绑分支块 (ICBBB) 可以是左侧 (CLBBB) 或右侧 (CRBBB).
- 由于异步,CLBBB与心室功能障碍有关.
- 曾经被认为是良性的CRBBB,现在与不良的心血管结果有关.
研究的目的:
- 为了评估心脏机械同步和静心/静心功能的患者与孤立的CRBBB.
- 为了比较隔离的CRBBB患者与隔离的CLBBB患者的心脏同步和功能.
主要方法:
- 一项涉及44名隔离CRBBB患者,44名隔离CLBBB患者和42名健康对照者的横截面研究.
- 胸外回声心脏成像用于评估右心室 (RV) 和左心室 (LV) 机械分散,全球纵向应变 (GLS) 和扩张功能 (E / e).
- 统计分析包括ANOVA,皮尔森相关性和线性回归.
主要成果:
- 与健康对照组相比,孤立的CRBBB患者显示RV机械分散显著增加,RV和LV GLS减少,E/e'升高.
- 与孤立的CLBBB患者相比,孤立的CRBBB患者具有较大的RV机械分散,三管E/e升高,并减少RVGLS.
- RV机械分散与RV GLS独立相关,而RV GLS和心房同步预测了CRBBB患者的LV GLS.
结论:
- 孤立的CRBBB患者表现出心脏机械同步和心室功能受损,与孤立的CLBBB患者相比,RV功能障碍更明显.
- 右心室内同步是独立预测RV静脉缩功能障碍在孤立的CRBBB.
- 心房心室同步和RV缩功能是LV缩功能的独立预测因素,需要对孤立的CRBBB进行全面的心声回声评估和监测.
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