在接受胃肠道癌症手术的老年患者中,术前的萨尔科佩尼亚和术后的妄想之间存在关联
Bo Dong1,2, Dongdong Yu1, Huanhuan Zhang1
1Department of Anesthesiology, Hebei General Hospital, Shijiazhuang, Hebei, China.
Frontiers in aging neuroscience
|August 15, 2024
概括
在接受胃肠道手术的老年患者中,手术前的sarcopenia与手术后的妄想有关. 早期识别肉类症可以帮助预测妄想风险.
科学领域:
- 老年医学 老年医学
- 手术瘤学手术瘤学
- 神经学 神经学
背景情况:
- 手术后痴呆症 (POD) 是手术后的一种常见的神经并发症,与患者的不良结果有关.
- 与年龄相关的肌肉质量和功能丧失,已被认为是POD的潜在预测因素.
- 在胃肠癌手术患者中,手术前的肉类和POD之间的确切关系需要进一步调查.
研究的目的:
- 调查手术前的肉类和POD发生在接受胃肠癌手术的老年患者之间的相关性.
- 为了确定这种患者群体中萨科佩尼亚是否是POD的独立风险因素.
主要方法:
- 接受胃肠道癌症手术的老年患者 (≥60岁) 使用ISarcoPRM标准 (超声波肌肉质量,椅子站测试功能和手握强度) 进行了评估.
- 在手术后7天内或出院前,使用混乱评估方法 (CAM) 或CAM-ICU诊断了术后妄想症.
- 使用多变量逻辑回归和ROC曲线分析来评估POD手术前肉症的关联性和预测价值.
主要成果:
- 在130名患者中,43人患有手术前的肉症,24人 (18.5%) 患有POD.
- 手术前的肉类是独立与POD相关的,即使在调整年龄,认知状态 (迷你精神状态检查) 和手术内输血后.
- 使用手术前肉症预测POD的ROC曲线下的面积为0.680.
结论:
- 根据ISarcoPRM标准的定义,手术前的肉是胃肠癌手术后老年患者手术后痴呆症的独立预测因素.
- 这些发现凸显了在手术前评估老年患者的肉症的重要性,以确定那些患有 Delirium 风险较高的人.
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