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Murine Fetal Echocardiography
Published on: February 15, 2013
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通过胎儿心脏量化技术评估胎儿心脏形态和功能的评估,在正常的第二和第三季度
Wenjing Hu1, Mingyue Wang2, Jinyan Bian2
1Department of Ultrasound, The Fourth Affiliated Hospital of Soochow University, Suzhou, China.
Translational pediatrics
|August 15, 2024
概括
胎儿心脏量化 (胎儿HQ) 技术显示,胎儿心脏大小随着妊娠年龄的增加而增加,而像射出分数这样的功能参数则减少. 这种斑点追踪方法有助于评估妊娠中后期胎儿心脏发育.
科学领域:
- 心脏病学 心脏病学
- 胎儿医学 胎儿医学
- 医学成像技术 医学成像技术
背景情况:
- 胎儿心脏评估对于理解产前发育至关重要.
- 胎儿心脏量化 (Fetal HQ) 是一种新兴的斑点跟踪技术,用于分析胎儿心室形态和功能.
- 评估正常的胎儿心脏发育为识别潜在异常提供了基线.
研究的目的:
- 利用胎儿HQ来评估妊娠中期到晚期正常胎儿心脏的结构和功能变化.
- 使用胎儿HQ.建立胎儿心脏参数的规范性数据.
- 为了为胎儿心脏斑点跟踪的临床应用奠定基础.
主要方法:
- 胎儿HQ被用来评估500个正常胎儿在不同的妊娠年龄 (GA).
- 测量的关键参数包括心脏大小,全球球形度指数 (GSI),中风体积 (SV),心脏输出 (CO),喷射率 (EF),全球纵向应变 (GLS),部分面积变化 (FAC),末端透气直径 (EDD),球形度指数 (SI) 和部分缩短 (FS).
- 胎儿被按GA分组,以观察心脏形态和功能的发育趋势.
主要成果:
- 胎儿心率随着GA的增加而下降 (P<0.05).
- 心脏尺寸参数和心室EDD随GA (P<0.05) 增加,EDD从底部到顶部不同.
- 腹腔功能参数 (EF,GLS,FAC) 一般与GA下降 (P<0.05),而SV和CO增加 (P<0.05). GSI和SI没有显著变化.
- 分段分数缩短 (FS) 显示了从底部到顶部的特定趋势,并且在心室之间有所不同.
结论:
- 胎儿HQ通过尺寸和细分参数提供对胎儿心脏生长和发育的定量评估.
- GSI和细分SI是评估胎儿心脏形态的可靠指数.
- 胎儿HQ评估的心室功能参数 (EF,FAC,GLS,FS) 对于评估胎儿心脏功能非常有价值.
- 胎儿HQ技术有效地评估胎儿在第二和第三个三个月的心脏生长和发育.
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