关于益生菌在治疗无氧性皮肤炎中的作用的德尔菲共识声明
Jayakar Thomas1, Maleeka Sachdeva2, Sandipan Dhar3
1Dermatology, Jayakar Thomas Skin Care Centre, Chennai, IND.
Cureus
|August 15, 2024
概括
益生菌可以作为一种有价值的补充疗法,用于治疗亚托皮炎 (AD). 这项研究发现,专家建议益生菌作为辅助治疗,以潜在地减少类固醇使用并改善阿兹海默症患者的治疗结果.
科学领域:
- 皮肤病学 皮肤病学
- 免疫学 免疫学 免疫学
- 微生物学 微生物学
背景情况:
- 无氧性皮肤炎 (AD) 是一种慢性炎症性皮肤疾病,具有复杂的病因发生,涉及遗传,屏障,免疫和微生物组因素.
- 益生菌通过调节免疫反应和增强上皮质屏障功能,显示出在过敏预防和管理方面的潜力.
- 了解当前关于亚丁病中益生菌的知识,态度和做法 (KAP) 对于基于证据的建议至关重要.
研究的目的:
- 建立基于共识的建议,关于益生菌在治疗亚型皮肤炎 (AD) 和其发作中的作用.
- 评估医疗保健专业人员关于在AD中使用益生菌的知识,态度和实践.
主要方法:
- 一项德尔菲介导的知识,态度和实践 (KAP) 调查,涉及175名成员的国家小组.
- 由九名专家组成的指导委员会制定的共识建议,分析文献评论和小组回复.
- 使用医疗保健研究和质量局 (AHRQ) 标准评估证据的强度和质量;建议要求≥70%的小组成员认可.
主要成果:
- 国家小组支持治疗阿尔茨海默病的益生菌,因为它们对营养状况,免疫调节和胃肠/皮肤健康有好处.
- 益生菌被推作为AD和相关发作的补充疗法,最好的补充时间为8-12周.
- 益生菌可以作为辅助疗法,以减少类固醇使用或在高风险病例中进行维护.
结论:
- 德尔菲介导的KAP方法为AD的益生菌使用提供了实用的见解.
- 益生菌被认为是一种潜在的有用辅助疗法,用于全面管理亚托皮炎及其发作.
- 将益生菌与传统治疗相结合,可能会增强AD治疗策略.
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