患有DSM精神障碍的人的长期结果 NOS NOS
Line Widing1, Carmen Simonsen1,2, Thomas Bjella1
1NORMENT, Norwegian Centre for Mental Disorders Research, Division of Mental Health and Addiction, Oslo University Hospital and University of Oslo, Oslo, Norway.
Schizophrenia bulletin open
|August 15, 2024
概括
精神病不规范症 (PNOS) 的长期结果比精神分裂症谱系障碍更好. 然而,PNOS的诊断结果仍然不可预测,显示患者的不稳定性和稳定性.
科学领域:
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
背景情况:
- 在DSM-IV中的"精神病不另有说明" (PNOS) 类别是研究不足的,对患者长期结局的数据有限.
- 了解PNOS的发展轨迹对于有效的临床管理和研究至关重要.
研究的目的:
- 调查最初被诊断为PNOS的个体的长期症状严重程度,全球功能,缓解/恢复率和诊断稳定性.
- 将这些结果与精神分裂症谱系障碍 (SSD) 和精神病双极性障碍 (PBD) 的结果进行比较.
主要方法:
- 一组32名初次治疗PNOS的参与者7-10年后使用结构化访谈重新评估.
- 对比分析包括患有狭窄精神分裂症谱系障碍 (SSD,n=94) 和精神病双极性障碍 (PBD,n=54) 的参与者.
- 缓解和恢复标准是基于既定的指导方针 (精神分裂症缓解工作组).
主要成果:
- 与SSD患者相比,患有PNOS和PBD的参与者在随访时表现出明显较低的症状严重程度和更好的整体功能.
- 在PNOS和PBD组中,与SSD组相比,观察到更高的症状缓解率和临床恢复率.
- 53%的PNOS参与者保留了他们的诊断,而其他人被重新诊断为SSD,情绪障碍或物质诱导的精神障碍.
结论:
- 对于PNOS和PBD的长期结果似乎比SSD更有利.
- 结果表明PNOS的诊断不稳定性,但也突出了子组内的稳定性.
- 根据最初的临床特征预测PNOS的长期诊断结果仍然具有挑战性.
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